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Hypoxia and Medicine

Hypoxia News

  • Ides of March arrives with Vomit, Hate and Twiztid Friday, March 12, 2010 @ 3:11AMMany of us know that Julius Caesar was warned to "beware the ides of March." But perhaps we don't know that the Ides of March (March 15) was the celebration for the Roman god of war, Mars. It appears however that the booking agent for Petaluma's Phoenix Theater knows that, because its weekend triple bill is enough to scare the bejesus out of most of all-ages suburbia.
  • NIH Awards More Than $800K in March to Fund Three miRNA-Related Research Projects Thursday, March 11, 2010 @ 1:45PMResearch into microRNAs has been an area of intense interest to the National Institutes of Health in recent months as far as extramural funding is concerned, and March has been no exception.
  • In Northwest waters, scientists track ‘dead zones’ Thursday, March 11, 2010 @ 2:22AMWASHINGTON – Lower levels of oxygen in oceans, particularly off the Northwest coast, could be another sign of fundamental changes linked to global climate change, scientists say.
  • PET-CT for response assessment and treatment adaptation in head and neck cancer Wednesday, March 10, 2010 @ 6:06PMPreferred treatment strategies for advanced-stage squamous cell carcinoma of the head and neck have shifted from surgery to organ-preservation approaches such as radiotherapy, which can be combined with chemotherapy or giving of biologically modifying molecules.
  • Parents of head-injured Victoria hockey player sue helmet maker, son struggles after hit Wednesday, March 10, 2010 @ 8:40AMDarren More used to be an outgoing, fun-loving high school student who loved hanging out with friends, driving his vintage car and playing hockey — but after sustaining a head injury during a hockey game five years ago, the 22-year-old has yet to graduate.
  • Lorus Therapeutics Announces Allowance of a Patent on its Small Molecule Program Wednesday, March 10, 2010 @ 7:30AMAustralian Patent Provides Broad Protection of its Small Molecule Drug Candidates
  • Lorus Therapeutics Announces Allowance of a Patent on its Small Molecule Program Wednesday, March 10, 2010 @ 7:20AMTORONTO, ONTARIO-- - Lorus Therapeutics Inc. , a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today announced the allowance of an Australian patent for novel compounds from its small molecule program.
  • Lorus Therapeutics Announces Allowance of a Patent on its Small Molecule Program Wednesday, March 10, 2010 @ 7:20AMTORONTO, ONTARIO--(Marketwire - 03/10/10) - Lorus Therapeutics Inc. (TSX: LOR - News ) ("Lorus"), a biopharmaceutical company specializing in the discovery, research and development of pharmaceutical products and technologies for the management of cancer, today announced the allowance of an Australian patent for novel compounds from its small molecule program. The Australian patent provides ...
  • Professor Discovers Link Between Low Oxygen Levels In Body And Cancer-Aiding Protein; Could Help Treatments For ... Wednesday, March 10, 2010 @ 6:29AMWhat began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma. Dolores Takemoto, a Kansas State University professor of biochemistry who was researching protein kinase C gamma in the lens of the human eye, found her work taking a fascinating turn when she discovered a correlation ...
  • Lowering levels of Coonexin46 with use of siRNA will help prevent tumor formation Wednesday, March 10, 2010 @ 1:42AMWhat began as research into how diabetics could possibly preserve their eyesight has led to findings that could prolong the vision of children afflicted with retinoblastoma.
  • Worries rise as ocean oxygen levels sink Monday, March 8, 2010 @ 1:45AMWASHINGTON - Lower levels of oxygen in oceans, particularly off the Northwest coast, could be another sign of fundamental changes linked to global climate change, scientists say.
  • Genome sequenced for amoeba that flips into free-swimming cell Sunday, March 7, 2010 @ 7:40AMScientists have sequenced the genome of a weird creature that exists as an amoeba until the food runs out, then turns into a two-tailed swimmer to find new hunting grounds. The organism, called Naegleria, is an early eurkaryote -- a cell with a nucleus and internal organs -- and could shed light on the origin of complex cells like those in humans. With video
  • Naegleria Genome Sheds Light On Transition From Prokaryotes To Eukaryotes Saturday, March 6, 2010 @ 5:12AMIn the long evolutionary road from bacteria to humans, a major milestone occurred some 1.5 billion years ago when microbes started building closets for all their stuff, storing DNA inside a nucleus, for example, or cramming all the energy machinery inside mitochondria...
  • WHOI grant will aid forecasts of red tide Saturday, March 6, 2010 @ 1:13AMWOODS HOLE — More than a half-million dollars in federal money is headed to the Woods Hole Oceanographic Institution to support research into the forecasting of future red tide outbreaks in New England waters.
  • Genome Sequencing Complete On Naegleria Gruberi Amoeba Thursday, March 4, 2010 @ 3:08PMNaegleria genome sheds light on transition from prokaryotes to eukaryotesIn the long evolutionary road from bacteria to humans, a major milestone occurred some 1.5 billion years ago when microbes started building closets for all their stuff, storing DNA inside a nucleus, for example, or cramming all the energy machinery inside mitochondria.Scientists have now sequenced the genome of a weird ...
  • Threshold Pharmaceuticals Reports Fourth Quarter and Year End 2009 Financial Results Thursday, March 4, 2010 @ 3:00PMREDWOOD CITY, Calif. -- Threshold Pharmaceuticals, Inc. today reported financial results for the fourth quarter and the year ended December 31, 2009.
  • Plodding amoeba flips into free-swimming flagellate: Naegleria genome sheds light on transition from prokaryotes to ... Thursday, March 4, 2010 @ 12:25PMScientists have sequenced the genome of a weird creature that exists as an amoeba until the food runs out, then turns into a two-tailed swimmer to find new hunting grounds. The organism, Naegleria, is an early eukaryote -- a cell with a nucleus and internal organs -- and could shed light on the origin of complex cells like those in humans, according to an analysis.
  • Genome sequencing complete on plodding amoeba that flips into free-swimming flagellate (w/ Video) Thursday, March 4, 2010 @ 12:13PMIn the long evolutionary road from bacteria to humans, a major milestone occurred some 1.5 billion years ago when microbes started building closets for all their stuff, storing DNA inside a nucleus, for example, or cramming all the energy machinery inside mitochondria.
  • UI professors rally against synthetic nitrogen fertilizer Thursday, March 4, 2010 @ 12:13AMWhile some people may think synthetic nitrogen fertilizer improves soil quality, three University professors challenged this belief with their analysis of soil from the Morrow Plots.
  • Teoh Beng Hock inquest: Pathologist unable to dismiss possibility of strangulation Tuesday, March 2, 2010 @ 10:28AMSHAH ALAM: A government pathologist who performed the second autopsy on Teoh Beng Hock, was unable to dismiss the possibility the latter had been strangled and if so, that the strangulation could have resulted in Teoh losing consciousness prior to his fall.
  • yes... Tuesday, March 2, 2010 @ 10:28AMIn reply to Teoh Beng Hock inquest: Pathologist unable to dismiss possibility of strangulation : yes...
  • I think they are MMed(Path) Tuesday, March 2, 2010 @ 10:28AMIn reply to Teoh Beng Hock inquest: Pathologist unable to dismiss possibility of strangulation : I think they are MMed(Path) local--lah....perhaps time to tie up our MMed exams to that of the Royal College in the UK...like what the Singaporeans, and the Hong Kongers are doing......
  • In Mouse Model Overexpression Of ARD1A Gene Reduces Tumor Size And Number Tuesday, March 2, 2010 @ 10:26AMOverexpression of the ARD1A gene (arrest-defective protein 1225) in mice reduced the number and size of both primary tumors and metastases, researchers report in a new study published online March 1 in the Journal of the National Cancer Institute. ARD1A blocks the expression of VEGFA (vascular endothelial growth factor A), an important mediator of blood vessel growth in tumors. It regulates ...
  • Data from Two Phase III Studies of Merck's Investigational Asthma Drug Presented at American Academy of Allergy ... Tuesday, March 2, 2010 @ 9:45AMNEW ORLEANS----Data from two Phase III studies of Merck’s investigational fixed-dose combinations of mometasone furoate and formoterol fumarate were presented by researchers today in two poster presentations at the American Academy of Allergy, Asthma & Immunology annual meeting.
  • Overexpression of ARD1A gene reduces tumor size and number in mice Monday, March 1, 2010 @ 10:50PMOverexpression of the ARD1A gene (arrest-defective protein 1225) in mice reduced the number and size of both primary tumors and metastases, researchers report in a new study published online March 1in the Journal of the National Cancer Institute.
  • Ovarian cancer research Monday, March 1, 2010 @ 8:24PMOvarian cancer has a high mortality rate as the disease is often not diagnosed until it's in the advanced stage and has spread
  • News brief: Overexpression of ARD1A gene reduces tumor size and number in mice Monday, March 1, 2010 @ 3:34PM( Journal of the National Cancer Institute ) Overexpression of the ARD1A gene (arrest-defective protein 1225) in mice reduced the number and size of both primary tumors and metastases, researchers report in a new study published online March 1 in the Journal of the National Cancer Institute.
  • Pathologist cannot ascertain whether Beng Hock was strangled Monday, March 1, 2010 @ 7:33AMSHAH ALAM: A pathologist told the Teoh Beng Hock inquest here today that he could not ascertain whether Teoh suffered asphyxiation due to strangulation or to being choked.
  • Teoh Beng Hock case: Pathologist unable to dismiss possibility of strangulation (Updated) Monday, March 1, 2010 @ 5:05AMSHAH ALAM: A government pathologist who performed the second autopsy on Teoh Beng Hock, was unable to dismiss the possibility the latter had been strangled and if so, that the strangulation could have resulted in Teoh losing consciousness prior to his fall.
  • [NEWS ] PATHOLOGIST CANNOT-2 Monday, March 1, 2010 @ 4:19AMDr Shahidan agreed with Malik's suggestion that if a person suffered from a "mild or modest" diffused cerebral hypoxia, a condition where the brain tissues did not get enough oxygen due to strangulation, the person could suffer confusion and even fainting.
  • Wilcox: A tactical company Monday, March 1, 2010 @ 1:14AMNEWINGTON — Instead of outsourcing jobs overseas, Wilcox Industries Corp. Chief Executive Officer James W. Teetzel said he's attracting foreign companies to America.
  • ART will Introduce Active Release Techniques into Chinese Hosiptals Sunday, February 28, 2010 @ 12:24PMActive Release Techiques ART - The Gold Standard in Soft Tissue TreatmentART is working with CFM to introduce its unique soft tissue treatment into Chinese hospitals. It will be a perfect fit for the West to meet the East, which will benefit more people who is looking for soft tissue treatment.What is Active Release Techniques ART to PatientsART...
  • DGAP-Media: TAVARGENIX GmbH: Inhibition of carbohydrate fermentation leads to sensitivity to chemo- and radiation ... Sunday, February 28, 2010 @ 10:41AMDJ DGAP-Media: TAVARGENIX GmbH: Inhibition of carbohydrate fermentation leads to sensitivity to chemo- and radiation therapy in cancer cells TAVARGENIX ...
  • DGAP-Media: TAVARGENIX GmbH: Inhibition of carbohydrate fermentation leads to sensitivity to chemo- and radiation ... Sunday, February 28, 2010 @ 10:09AMDissemination of a Media Release, transmitted by DGAP - a company of EquityStory AG. The issuer is solely responsible for the content of this announcement.
  • Active Release Techniques Sunday, February 28, 2010 @ 5:34AMAbout ART :What is Active Release Techniques ART to PatientsART is a patented, state of the art soft tissue system/movement based massage technique that treats problems with muscles, tendons, ligaments, fascia and nerves. Headaches, back pain, carpal tunnel syndrome, shin splints, shoulder pain, sciatica, plantar fasciitis, knee problems, and tennis...
  • Lethal drug combos a growing problem in Anderson County Saturday, February 27, 2010 @ 9:20PMANDERSON COUNTY —Christopher Whiten, a young man with everything to live for, swallowed a mix of painkillers the night of Nov. 3, 2009, went to bed and died.By the time Whiten’s fiancee, Carley Smith, who slept on the living room couch because of Chris’s “unusually loud snoring,” came into the bedroom to wake him the following morning, he had been dead for hours.He was the 36th person in ...
  • Akebia Announces Initiation Of Phase 1b Clinical Study Of AKB-6548 Friday, February 26, 2010 @ 11:23PMAkebia Therapeutics, Inc., a small molecule discovery and development company focused on anemia and vascular disorders, announced that it has initiated dosing for a phase 1b multi-dose clinical trial of AKB-6548, an orally bioavailable hypoxia-inducible factor-prolyl hydroxylase (HIF-PH) in development for anemia. The phase 1a study of AKB-6548 demonstrated a dose-related increase in ...
  • Cincinnati’s Akebia starts phase 1b clinical trial for anemia drug Friday, February 26, 2010 @ 2:12PMCINCINNATI, Ohio — Small molecule discovery and development company Akebia Therapeutics Inc. has started a second phase 1 clinical trial of its anemia drug — another baton hand-off in a race with big drug companies to get to market first with a safer, more effective, less expensive oral treatment.
  • Waiting to Inhale: Deep-Ocean Low-Oxygen Zones Spreading to Shallower Coastal Waters Tuesday, February 23, 2010 @ 3:53PMA plague of oxygen-deprived waters from the deep ocean is creeping up over the continental shelves off the Pacific Northwest and forcing marine species there to relocate or die. Since 2002 tongues of hypoxic, or low-oxygen , waters from deeper areas offshore have slipped into shallower near-shore environments off the Oregon coast, though not close enough to be oxygenated by the waves. The ...
  • "Choking Game" Awareness and Participation Among 8th Graders--Oregon, 2008 [From the Centers for Disease Control and ... Tuesday, February 23, 2010 @ 3:35PMJAMA. 2010;303(8):723-725.
  • Cancer Recurrence Treatment Shows Promise In Prevention Tuesday, February 23, 2010 @ 11:15AMGlioblastoma is one of the most deadly human brain cancers.
  • New Treatment To Prevent Cancer Recurrence Shows Promise In Stanford Study Tuesday, February 23, 2010 @ 8:26AMGlioblastoma is one of the most deadly human brain cancers. Radiation can temporarily shrink tumors, but they nearly always recur within weeks or months and few patients survive longer than two years after diagnosis. Now scientists at the Stanford University School of Medicine studying the tumor in mice have found a way to stop the cancer cells from growing back after radiation by blocking its ...
  • New treatment to prevent cancer recurrence shows promise in study Monday, February 22, 2010 @ 10:23PMGlioblastoma is one of the most deadly human brain cancers. Radiation can temporarily shrink a tumor, but they nearly always recur within weeks or months and few patients survive longer than two years after diagnosis. Now scientists at the Stanford University School of Medicine studying the tumor in mice have found a way to stop the cancer cells from growing back after radiation by blocking its ...
  • Applying Environmental Law to the Farm Bill Sunday, February 21, 2010 @ 5:43PMIf you have ever wondered just where the spark may come for new theories of environmental litigation, and ways to reshape agricultural policy in the process, well then I have a good example for you today.
  • Carbonic Anhydrase IX Expression In Prostate Cancer Sunday, February 21, 2010 @ 6:40AMUroToday.com - Tumor hypoxia plays a role in tumor progression and chemotherapy resistance through reduced apoptosis, increased proliferation and angiogenesis. Hypoxic cell metabolism switches to anaerobic glycolysis and the production of acidic metabolites that facilitate cell survival and tumorigenesis. The pH of solid tumors is more acidic than normal tissue and impairs the uptake of weakly ...
  • Exploring The Limits: Understanding The Challenges Facing Winter Olympic Champions Monday, February 15, 2010 @ 5:22AMAs the world turns its sporting gaze towards Vancouver for the 2010 Winter Olympics, The Physiological Society journal Experimental Physiology marks the occasion with a special issue exploring the biological and environmental challenges elite winter athletes must overcome to win gold. "When most people think about these games we conjure up glorious images of snow and high mountains", said co ...
  • Deaths/causes | Dec. 22 - Feb. 1 | PUBLIC RECORDS Sunday, February 14, 2010 @ 12:23AMAgnew, James Melvin; 66, Evansville, Jan. 22, cardiac arrest, respiratory failure, pneumonia, lung cancerArvin, Martha A.; 68, Petersburg, Ind., Jan. 23, acute myocardial infarction, ischemic cardiomyopathy, end-stage heart diseaseBays, Christopher Michael; 27, Evansville, Jan. 19, coroner — respiratory arrestBeck, Jacen A.; 35, Evansville, Jan. 27, cardiomyopathy, end-stage renal disease ...
  • Journal explores biological and environmental challenges in elite winter sports Thursday, February 11, 2010 @ 12:25AMAs the world turns its sporting gaze towards Vancouver for the 2010 Winter Olympics, The Physiological Society journal Experimental Physiology marks the occasion with a special issue exploring the biological and environmental challenges elite winter athletes must overcome to win gold.
  • Research Could Lead To Way To Halt Deadly Immune Response Wednesday, February 10, 2010 @ 10:13AMResearchers have teased out the molecular process that can shut down a marauding, often deadly immune response that kills thousands each year who suffer battlefield casualties, heart attacks, strokes, automobile accidents and oxygen deprivation, according to an article published in the January edition of Molecular Immunology. The article provides additional detail about the enormously complex ...
  • Research Could Help Halt Deadly Immune Response Wednesday, February 10, 2010 @ 10:11AMScientists report further progress in study of complement reactionResearchers have teased out the molecular process that can shut down a marauding, often deadly immune response that kills thousands each year who suffer battlefield casualties, heart attacks, strokes, automobile accidents and oxygen deprivation, according to an article published in the January edition of Molecular Immunology.The ...