Hypoxia and Medicine

what is ischemia reperfusion injury?

Public Comments

1. AllI know is that ischemia means lack of oxygen. I don't know what reperfusion is, but fusion is joining together. I hope someone with more knowlege answers you.
2. When a part of the body is deprived of oxygen...for example, from a blocked artery, it uses alternative maetabolic pathways to generate energy...this leads to potential toxic metabolities, free radicals, low pH states...when the blockage is cleared, then all the "bad chemicals" are now free to flow into the nearby tissues...this can actually affect and cause the noraml tissue to get injured or behave improperly...as in reperfusion cardiac arrhythmias after using clotbustung drugs