Hypoxia and Medicine

How do you find the amount of oxygen released to muscles in physiology?

Assume that at rest the avg blood flow to the skeletal muscle is 100 ml/min with about 20 ml of oxygen per 100 ml of arterial blood (at sea level). What about at maximum exercise or at high elevation? How to calculate this isn't making any sense to me and I've found no help anywhere else. I know you need to use a hemoglobin oxygen saturation curve, but I'm not sure how to read it. Only helpful suggestions--no criticism, please!

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