Hypoxia and Medicine

Which part of cardiac output is most likely to be affected by ischemia of myocardium - i.e. from a MI?

When a myocardial infarction occurs, what component of cardiac output is most likely to be affected as a result of the ischemic tissue? Is it the afterload, preload, or contractility? I'm thinking it's either the afterload or contractility.

Public Comments

1. In a myocardial injury, a percent of the heart muscle is lost and the heart cannot work successfully, so the after load is affected(the amount that stays in the heart)and this is added to the amount of blood that comes to the heart , so the preload is affected also. If Cardiogenic Shock sets in: Cardiogenic Shock, which is defined as shock resulting from a decline in cardiac output secondary to serious heart disease such as myocardial infarction. In cardiogenic shock, the preload and the after load are increased, while myocardial contractility is decreased.
2. the contractility, and eventually the preload (seeing as your cardiac output will reduce and hence less blood returning to the right atrium)..this will also eventually affect the afterload.