Summary: (from ischemic necrosis due to hypoxia, DIC and renal vasoconstriction). Clinical signs of a severe acute hemolytic reaction are, unfortunately, non-specific and include tachycardia, dyspnea, collapse, hypotension, salivation, tremors, convulsions, weakness, vomiting and pyrexia. Acute intravascular hemolysis produces hemoglobinemia (as shown in the image on the left) and
Image Dimensions: 128 x 157
Image originally found here.